Importantly, expression of the most frequently mutated genes in T cell lymphoma or leukemia (i.e., DNMT3A, TET2, JAK, NOTCH1, CDKN2A, PTEN, and FBXW7) was not altered in miR-H18-BCMA CAR T cells.46 The gene discussed is NOTCH1; the disease is T-cell non-Hodgkin lymphoma.