For example, the genetically dystonic dt rat gave the initial impression of cerebellar activity in rodents with dystonia [23] and the Dyt1 null mice were key in uncovering a network impact [16], whereas knockin of a mutant Dyt1 sequence revealed circuit, behavioral, and developmental effects in dystonia [20], phenotypes which were interestingly also seen in a forebrain knockout of Dyt1 [60]. This evidence concerns the gene TOR1A and Dystonia.