SOAT1 and colorectal carcinoma: Consistently, knockdown of SOAT1 inverted the enhancement of proliferation, migration and invasion induced by circLDLR overexpression (Fig. 6I, J, Supplementary Fig. S6C, D), and reversed the promotive consequence of circLDLR overexpression on T-CHO and LDL-C contents in CRC cells (Fig. 6K).