EDN1 and glaucoma: Correlation analysis for AqH and plasma levels of ET-1 in the glaucoma group (Table 2; more detail in Supplemental Table 3) showed that elevated AqH ET-1 level did not correlate with the IOP or lens status, but correlated significantly positively with the number of topically applied antiglaucoma medications (p < 0.01, r = 0.374; Supplemental Table 3).