Both superRCA and ddPCR assays recorded even higher levels of the IDH2 p.R172K mutation in this sample compared to the sample taken at AML diagnosis, confirming the presence of clonal hematopoiesis in the setting of peripheral cytopenia, also named clonal cytopenia of undetermined significance, prior to the AML diagnosis for this patient. Here, IDH2 is linked to acute myeloid leukemia.