Levels of CXCL8 were found to be significantly higher in samples, such as brain tissue, plasma, and CSF, obtained from AD patients as compared to healthy controls (Alsadany et al. 2013; Ashutosh et al. 2011; Corrêa et al. 2011; Galimberti et al. 2006; Sokolova et al. 2009). This evidence concerns the gene CXCL8 and Alzheimer disease.