The immunohistochemical data showed that DUB1 expression was significantly higher in gastric cancer samples, and DUB1 expression was correlated with lymph node metastasis and higher clinical stage (P < 0.001, P < 0.001, and P < 0.001, respectively; Fig. 1D-1E). Here, USP36 is linked to metastatic malignant neoplasm in the lymph nodes.