To explore the mechanisms of α-Gal antigen deficiency and anti-Gal antibody presence in GGTA1 gene-edited rabbits, we used qRT–PCR to assay GGTA1 gene expression in the lung tissue of 3 F2 GGTA1 gene-edited rabbits and 3 WT rabbits. The gene discussed is GGTA1; the disease is hyperinsulinemic hypoglycemia, familial, 4.