On the other hand, significant negative correlations were observed between glucagon levels and HUI (r = -0.74, P < 0.01) and nocturnal hypoglycemia (r = -0.69, P < 0.01) in patients with FCPD and unaware of hypoglycemia, coupled with significant negative correlations of glucagon levels with the SD, MAGE and GV-hypoglycemia indices in this group. The gene discussed is GCG; the disease is Hypoglycemia.