Correlation analysis for glucagon secretion (AUC-glucagon) in the UNAWARE group showed significantly negative correlations with the HUI (r = -0.74, P < 0.05), nocturnal hypoglycemia episodes (r = -0.69, P < 0.05) and GV indices namely MAGE (r = -0.66, P < 0.05) Standard Deviation for the mean of glucose values recorded on the sensor (r = -0.62, P < 0.05), GRADE-hypo (r = -0.59, P < 0.05) and TSB < 70 (r = -0.60, P: < 0.05). Here, GCG is linked to Hypoglycemia.