IL6 and bacterial infectious disease: In the total study population of critically ill surgical patients (n = 200), IMX-BVN-3 bacterial scores had an AUROC of 0.84 (95% CI, 0.77-0.90), a performance that was similar to that for procalcitonin levels (AUROC, 0.85 [95% CI, 0.79-0.90]; P = .79) and significantly better than that for both IL-6 levels (AUROC, 0.67 [95% CI, 0.58-0.75]; P < .001) and total white blood cell count (AUROC, 0.68 [95% CI, 0.59-0.77]; P = .003) for the ability to discriminate for the presence of bacterial infection (Figure 3A).