After analyzing PGM5 expression pattern in prostate cancer tissues, we found that in cancer tissues, 4 cases were strong (5–6 points), 19 cases were moderate (3–4 points), 37 cases were weak (1–2 points), and 11 cases were negative (0 point), while in para-cancer tissues, we found that 33 cases were strong, 24 cases were moderate, 14 cases were weak, and 0 case was negative. The gene discussed is PGM5; the disease is prostate carcinoma.