High expression of lncRNA RP1 in breast cancer cells and tissues is closely associated with malignant progression and poor prognosis in breast cancer patients, which indicated that RP1 could promote EMT and maintain the stemness states of breast cancer cells by binding to the p-4E-BP1/eIF4E complex, reduced the translation efficiency of p27kip1 mRNA, and repressed p27kip1 protein expression [37]. The gene discussed is EIF4E; the disease is breast cancer.