A single-nucleotide polymorphism (SNP) in the ZDHHC8 gene has been implicated in increased susceptibility to schizophrenia (Chen et al., 2004; Mukai et al., 2004), while hemizygous microdeletion in the chromosomal locus 22q11, which encodes a number of genes including ZDHHC8, is one of the highest known genetic risk factors to developing schizophrenia (Karayiorgou et al., 2010). Here, ZDHHC8 is linked to schizophrenia.