Only five proteins, ceruloplasmin (CERU), fetuin A (FETUA), succinate‐‐CoA ligase [ADP/GDP‐forming] subunit alpha (SUCA), non‐secretory ribonuclease (RNAS2) and eosinophil cationic protein (ECP), named also RNAS3, were differential more identified in obesity than non‐obesity (Table S2) with statistical significance (p < .05). This evidence concerns the gene RNASE3 and obesity due to melanocortin 4 receptor deficiency.