Therein, a total of six LncRNA/RBP/EXTL3 mRNA networks containing the FENDRR/DGCR8/EXTL3 axis, the FENDRR/HNRNPA1/EXTL3 axis, the FENDRR/HNRNPC/EXTL3 axis, the FENDRR/RBFOX2/EXTL3 axis, the FENDRR/SRSF1/EXTL3 axis, the FENDRR/U2AF2/EXTL3 axis, were eventually identified in this article for EXTL3-related mechanisms for PCa. This evidence concerns the gene HNRNPC and posterior cortical atrophy.