Among these, involvement of EPOR (Erythropoietin receptor; involved in JAK2-MAPK/ PI3K/ STAT signaling), DDB2 (Damage specific RNA binding protein 2; involved in UV damage repair and Xeroderma), ROBO3 (Roundabout guidance receptor 3; involved in migration or neurite outgrowth), and MT1G (Metallothionein 1G; involved in protection against oxidative stress and metals) in various cancers is well-documented with hundreds of publications. This evidence concerns the gene JAK2 and cancer.