This included known cancer type-specific gene fusions such as TMPRSS2-ERG for Prostate39, EML4-ALK for Lung_NonSmallCell40, KIAA1549-BRAF for CNS_PiloAstro (pilocytic astrocytomas)41, and FUS-DDIT3 for Sarcoma_Lipo42. The gene discussed is ALK; the disease is cancer.