To study if chemoresistance in the presence of Q was via induction of PRDX1, we next inhibited PRDX1 using siRNA in pancreatic cancer cells SU86.86 and determined effect on cell viability in the presence of paclitaxel ± Q. Silencing was verified by qPCR (Supplementary Figure 4D). Here, PRDX1 is linked to familial pancreatic carcinoma.