We demonstrated that FABP5 is highly expressed in human HCC tissues, which confirms the findings of previous studies.21 Moreover, we found that FABP5 was involved in HCC cell proliferation, migration, and invasion, which is in agreement with a previous study.22 The specific mechanisms underlying the upregulation of FABP5 in various human tumors have also been discussed for other cancers. This evidence concerns the gene FABP5 and hepatocellular carcinoma.