In prostate cancer, FABP5 activates the NF-κB signaling pathway by increasing reactive oxygen species (ROS) and protein kinase C production and induces inflammation and the production of IL-6 and IL-8.16 FABP5 can promote angiogenesis in HCC by activating the IL6/STAT3/VEGFA pathway.17 However, the specific molecular mechanism by which FABP5 regulates the proliferation and migration of hepatoma cells has not been clearly defined, and it needs to be further elucidated. Here, CXCL8 is linked to hepatocellular carcinoma.