miR-889 promotes colon cancer cell proliferation by inhibiting DAB2IP transcription.32 miR-889 can inhibit the expression of myeloid cell nuclear differentiation antigen (MNDA) targets cell cycle regulation in order to influence the progression of osteosarcoma.33 However, miR-889 has been shown to have the opposite effect on non-small cell lung cancers (NSCLCs). The gene discussed is MNDA; the disease is osteosarcoma.