TNF and squamous cell carcinoma: In this regard, we evaluated the uptake of rhodamine-labeled CCPM decorated with increasing cRGD densities (1, 3.6, and 5 mol%) against ανβ3-integrinhigh (i.e., 4T1 breast cancer and TNFα-activated HUVEC), ανβ3-integrinlow cells (i.e., A431 epidermoid carcinoma cell line), and ανβ3-integrinintermediate cells (non-activated HUVEC).