Work-up for hypercalcemia revealed suppression of parathyroid hormone (PTH; 6 pg/dL; n: 18–80 pg/dL), normal PTH-related protein (PTH-RP; 20 pg/dL; n: 0–23 pg/dL); decreased 25-hydroxyvitamin D (9.2 ng/d; n: 30–100 ng/dL), 1,25-dihydroxyvitamin D total, D2, and D3 (< 8 pg/mL; n: 19.9–79.3 pg/dL). The gene discussed is PTH; the disease is hypercalcemia disease.