SYNGAP1 and Intellectual disability: SYNGAP1-related Intellectual Disability (SYNGAP1-ID) is a rare condition that is characterized by global developmental delays and often accompanied by epilepsy and autism (Squire et al., 1990; Hamdan et al., 2011; Holder et al., 2019; Jimenez-Gomez et al., 2019; Vlaskamp et al., 2019).