UBD and congenital secretory chloride diarrhea 1: Additionally, we showed that despite not harboring genetic alterations observed in HCC, CLD samples showed hypomethylation of genes such as HDAC11, which is highly expressed in immune cells (47), UBD (FAT10), involved in the inflammatory response and immune cell infiltration (47, 48), and TAGLN2 that controls liver cancer cell motility (47–49).