In Figure 4D, B16 and B.m+B16 groups showed no significant (p > 0.0332) difference in the proportion of macrophages in the tumor microenvironment, but the B.m+B16 group exhibited a significant (p ≤ 0.0021) increase (∼ 63%) in the median fluorescence intensity (MFI) of MHC-II and a decrease (∼ 44%, p ≤ 0.0332) in the MFI of CD206 relative to the B16 group. Here, MRC1 is linked to neoplasm.