The KEGG enrichment showed that the targets were associated with transcriptional misregulation in cancer, and the genes including MEF2C, CCNT2, BCL11 B, PBX3, MLLT3, KLF3, FLI1, HOXA11, IGF1R, ELK4, MEIS1, NR4A3, SIX4, NSD2, and REL were enriched in this cellular pathway (Figure 3(b), P < 0.01). This evidence concerns the gene SIX4 and cancer.