It is known that PD-L1 in many tumors has high expression, including lung cancer, colorectal cancer, gastric cancer, melanoma, leukemia, stromal tumor, multiple myeloma, esophageal, ovarian, pancreatic, renal cell carcinoma, oral squamous cell carcinoma, and nasopharyngeal carcinoma [11–18]. The gene discussed is CD274; the disease is lung cancer.