Glodkowska et al. (15), compared the expression of BIRC family genes in chronic myeloid leukemia (CML) patients cells and normal hematopoietic cells, found a significant decrease in ILP-2 expression after the development of tyrosine kinase inhibitor resistance in chronic phase CML patients. Here, NAIPP2 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.