SNAI2 and breast carcinoma: However, when FBXW7 was repressed by estrogen receptor α (Erα) in breast cancer, high expression of C/EBPδ was revealed to attenuate the carcinogenicity of cancer cells through suppressing expression of the SNAI2, which is different from a previous research correlated with the role of C/EBPδ in breast cancer (34, 149).