We further validated this finding in pancancer datasets and found that plac1 was highly expressed in the D subtype in SKCM, colon adenocarcinoma, kidney renal papillary cell carcinoma, kidney renal clear cell carcinoma (KIRC), ovarian serous cystadenocarcinoma, lung squamous cell carcinoma, breast invasive carcinoma, thyroid carcinoma, and stomach adenocarcinoma (Figure 5D, IE/F vs. D, t-test). This evidence concerns the gene PLAC1 and invasive breast carcinoma.