PLAC1 and metastatic malignant neoplasm in the lymph nodes: In advance-stage lymph node metastasis patients, male patients, and oropharynx patients, plac1-positive patients had poorer outcomes (p = 0.040, 0.042, 0.028, and 0.015, respectively) (Figures 1I–L, Supplementary Figures S4C–G).