(33) established a nomogram for 1-, 3-, and 5-year RFS based on tumor size, tumor number, direct invasion, and triosephosphate isomerase (TPI1), while they did not provide treatment decisions for postoperative early and late recurrence, although they showed the prognostic model was accurate in predicting recurrence for ICC patients. This evidence concerns the gene TPI1 and intrahepatic cholangiocarcinoma.