ABCC2 and esophageal squamous cell carcinoma: In TE14 and TE5 cell lines, ABCC2 appearance was higher and showed powerful resistance to CDDP. ESCC cell lines that contain more ABCC2 show more resistance to CDDP than lower containment of ABCC2. To confirm the role of ABCC2 in drug resistance, the ABCC2 gene was silenced with siRNAs into the TE14 cell line raised reactivity to CDDP