MYC and B-cell chronic lymphocytic leukemia: Within the subgroups defined by the most common CLL-related recurrent cytogenetic aberrations, the cases with MYC gain reached the following frequencies – delATM: 10.0 % (8/80), delTP53: 14.8 % (4/27), del(13q): 5 % (10/201), +12: 0 % (0/30), delATM+delTP53: 16.6 % (1/6), and patients negative for the standard CLL-FISH probe panel: 4.2 % (2/48) (Figure 1A).