NFKB1 and breast cancer: In addition, overexpression of several miRNAs, such as miR-125b and miR-668, leads to NF-κB activation by targeting TNF alpha induced protein 3 (TNFAIP3/A20) and IκBα, respectively, thus promoting radioresistance in nasopharyngeal carcinoma (69) and in breast cancer (70).