Fang et al. showed that miR-1247-3p-carrying TEXs promote liver cancer stemness and chemoresistance via inhibition of beta-1,4-galactosyltransferase 3 (B4GALT3) and activation of β1-integrin–NF-κB pathway in fibroblasts (129). The gene discussed is B4GALT3; the disease is liver cancer.