UCA1 and colorectal cancer: Other two lncRNAs involved in drug resistance are lncRNA urothelial carcinoma-associated 1 (UCA1) and lncRNA prostate androgen-regulated transcript 1 (PART1); Yang et al. founded that exosomal UCA1 is associated with Cetuximab resistance in colorectal cancer and could predict clinical outcome of Cetuximab therapy (106), while Kang and collaborators demonstrated that lncRNA PART1 is able to confer resistance to Gefitinib in esophageal squamous cell carcinoma by inducing B-cell lymphoma 2 (Bcl-2) expression through inhibition of miR-129 (107).