Significant enrichment was observed in immune response and inflammation-related diseases such as SLE and FCγR-mediated phagocytosis and the TOLL-like receptor signaling pathway and other KEGG pathways (Figure 6C), TNFA signaling via NFKB, IL6 JAK STAT3 signaling, interferon γ response, interferon α response, and other Hallmark pathways (Figure 6D). The gene discussed is STAT3; the disease is systemic lupus erythematosus.