According to VIP scores, proteins identified as Lactoferrin, Coagulation factor V, Polyubiquitin-C, Immunoglobulin heavy variable 3-66, Inositol 1,4,5-trisphosphate receptor, MSN, Histone H2B type 1-J, cDNA FLJ56274, Kininogen 1 isoform, Talin-1, and Histone H1.5 made the most meaningful contributions to characterize the bone marrow plasma of MDS-EB patients. Here, H1-5 is linked to myelodysplastic syndrome.