As centrosomal protein of 55 kDa (CEP55), moesin (MSN), talin-1 (TLN1), and ubiquitin C (UBC) showed the highest differential abundances in MDS-RS vs. MDS-EB cases, a second phase of the research was carried out to analyze the expression of those respective genes in mononuclear cells of a distinct cohort of MDS patients. This evidence concerns the gene TLN1 and myelodysplastic syndrome.