They found that the metabolic features of lung cancer cells were altered by ALDH1A1 overexpression, and levels of most metabolites, such as glucose-6-phosphate, fructose 1,6-diphosphate, propionyl-CoA, malic acid, phosphatidylcholine, glycerol phosphatidylcholine, GMP, citrulline, and arginine succinic acid were increased. The gene discussed is ALDH1A1; the disease is lung carcinoma.