The results showed that KDELR1 expression significantly increased with the WHO grade in several cohorts, including mRNA-array_301, mRNA-array_325, and mRNA-array_693 of CGGA, TCGA_glioma, GSE4271, GSE4290, and GSE4412 (P < 0.05; Figures 4A–G). This evidence concerns the gene KDELR1 and central nervous system cancer.