In NSCLC, BJ1 co-cultured with A549 and HCC827 downregulated the expression of IDH3α, another marker of glycolysis in CAFs, compared to BJ1 in monoculture (Figures 2E, F), whereas no significant changes in IDH3α in carcinoma cells were observed (data not shown). Here, IDH3A is linked to non-small cell lung carcinoma.