We have shown that ADT carcinoma cells co-cultured with MCT4-knockdown (KD) BJ1 fibroblasts (BJ1-sgMCT4) and MCT4-KO MEFs have increased apoptotic rates and decreased proliferation compared to co-cultures with MCT4-expressing fibroblasts (BJ1-sgCTRL and WT-MEF) (Figure 9B). Here, SLC16A3 is linked to carcinoma.