Nuclear localization of PTEN and its lipid phosphatase activity contribute to the increased production and maturation of miR-125b and miR-203b by directly regulating the translocation of miRNA-processing enzymes Drosha and DGCR8 in the nucleus, which limits the abundance of MyD88, resulting in the suppression of sepsis-induced lung injury [65]. Here, PTEN is linked to Sepsis.