Wang et al. suggested that PTEN is upregulated in the plasma and peripheral blood mononuclear cells of patients with ARDS, which is probably due to the increased expression of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a multifunctional long noncoding RNA that interacts with miR-425 to induce cell apoptosis [68]. The gene discussed is MALAT1; the disease is acute respiratory distress syndrome.