PTEN and allergic asthma: Lee's group reported that the Korean red ginseng extract and its component nepetin could attenuate Th2-derived cytokines, eosinophil infiltration, and airway remodeling in the OVA-induced allergic asthma model, and the mechanism is implicated in PPARγ upregulation and PTEN-PI3K/Akt pathway inhibition by reducing the phosphorylation level of PTEN [136].