And connexin 43 (CX43) is crucial for macrophages’ conduction, and its abnormal expression and distribution will lead to the abnormality of the conduction of the cardiomyocytes, decreasing the conduction velocity and changing the anisotropy, producing arrhythmias (Peters et al., 1997; Morel et al., 2012; Zhang et al., 2014). Here, GJA1 is linked to Arrhythmia.