And connexin 43 (CX43) is crucial for macrophages’ conduction, and its abnormal expression and distribution will lead to the abnormality of the conduction of the cardiomyocytes, decreasing the conduction velocity and changing the anisotropy, producing arrhythmias (Peters et al., 1997; Morel et al., 2012; Zhang et al., 2014). This evidence concerns the gene GJA1 and cardiac arrhythmia.