Intriguingly, we found CD80 showed significantly higher expression in several cancers including BLCA (bladder urothelial carcinoma), BRCA (breast invasive carcinoma), CHOL (Cholangiocarcinoma), COAD (colon adenocarcinoma), ESCA (esophageal carcinoma), HNSC (head and neck squamous cell carcinoma), KIRC (kidney renal clear cell carcinoma), KIRP (kidney renal papillary cell carcinoma), STAD (stomach adenocarcinoma), and UCEC (uterine corpus endometrial carcinoma). This evidence concerns the gene CD80 and cholangiocarcinoma.