DSC2 and gonorrhea: Other possible biomarkers that hold immense potential in GC include actin-related protein 2/3 (APR 2/3), desmocollin 2 (DSC2), B7H6 ligand, neuropilin-1 (NPR-1), cancer-related antigens CA-72-4 and CA-19-9, and anion exchanger 1 (AF1) (Zhang Q. et al., 2016).