As observed in the immortalised cell line, IL-1β supplementation (100 pg/ml) in primary cells led to a significant increase in mineral deposition (2.91 ± 0.15 fold change compared to OM), while IL-8 (2 ng/ml) and IL-10 (100 pg/ml) did not produce any notable changes (Figure 4). The gene discussed is IL10; the disease is ocular melanoma.