IL-10 (100 pg/ml) supplementation did show a modest increase in ALP activity by day 10 only (1.07 ± 0.01 fold change compared to OM), while mineral deposition showed a transient decrease at day 14 (0.52 ± 0.12 fold change compared to OM), which recovered by day 21. This evidence concerns the gene IL10 and ocular melanoma.