IL1B and ocular melanoma: An increase in ALP activity in response to IL-1β was observed at day 7 and day 10 for all doses, although beyond 10 pg/ml the response was largely similar (Day 7: 1 pg/ml 1.14 ± 0.04, 10 pg/ml 1.29 ± 0.02, 100 pg/ml 1.28 ± 0.06, 1,000 pg/ml 1.35 ± 0.03 fold change compared to OM; Day 10: 1 pg/ml 1.16 ± 0.03, 10 pg/ml 1.23 ± 0.02, 100 pg/ml 1.24 ± 0.02, 1,000 pg/ml 1.19 ± 0.04 fold change compared to OM).