Several lncRNAs, such as BACE1-AS, 51A, BC200, and NDM29, have been found to be aberrantly expressed in AD compared with healthy controls and were involved in AD pathogenesis by the low-throughput experiments (Faghihi et al., 2008; Lin et al., 2008; Massone et al., 2012; Ciarlo et al., 2013). The gene discussed is BACE1; the disease is Alzheimer disease.