ANO1 and cystic fibrosis: In another study, knockdown of anoctamin 1 (ANO1 or TMEM16A), antioxidants, such as coenzyme Q10 (CoQ10) and idebenone, and ferrostatin-1 attenuated Pseudomonas aeruginosa-induced cell death in CF bronchial epithelial cells (Ousingsawat et al., 2021).