In a mouse model of ALI-induced by intestinal ischemia-reperfusion, Nrf2 expression can inhibit ferroptosis via modulation of telomerase reverse transcriptase (TERT), HO-1, and SLC7A11 levels (Dong et al., 2020; Dong et al., 2021). The gene discussed is SLC7A11; the disease is acute respiratory distress syndrome.