After adjusting for clinical features, including age, sex, tumor stage, and smoking, as well as the driver gene mutation (EGFR, KRAS, ALK, ROS1, BRAF, and TP53), the DRG served as an independent prognostic biomarker for predicting outcomes (OS, HR: 0.42 (0.30–0.58); DFS, HR: 0.43 (0.31–0.53), Table 1). This evidence concerns the gene TP53 and neoplasm.