Cystic fibrosis (CF) is a life-threatening, autosomal recessive hereditary disease caused by loss-of-function mutations of the cftr gene which encodes a chloride channel cystic fibrosis transmembrane conductance regulator (CFTR) (Riordan et al., 1989; O’Sullivan and Freedman, 2009; De Boeck and Amaral, 2016). The gene discussed is CFTR; the disease is cystic fibrosis.