In our study on the relationship between Slit-2 and inflammatory factors CRP and MCP-1 in GDM patients, we found that Slit-2 was positively correlated with CRP and MCP-1 in maternal peripheral blood and neonatal cord blood of GDM patients, suggesting that it may play a proinflammatory role in GDM through Slit 2/Robo1 axis (15). This evidence concerns the gene CRP and gestational diabetes.