A more recent study in MIN6 insulinoma cells and primary mouse and human islets showed that shRNA knockdown of KIF3A led to reduced ciliation and islet cell proliferation, where the absence of cilia may disrupt cell division, but short-term KIF3A gene silencing had no apparent effects on glucose-stimulated insulin secretion (19). The gene discussed is KIF3A; the disease is pancreatic insulinoma.