An interesting study on glioblastoma, where the authors make a distinction between MVs and exosomes, shows that only MVs secreted by BV2 or mice primary microglia can suppress migration and invasion capacity of glioblastoma cell line GL261, when microglia are treated with LPS and interferon (IFN)-γ (Grimaldi et al., 2019). This evidence concerns the gene IFNG and glioblastoma.